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Bionanoprobe

Hard x-ray scanning nanoprobe with cryogenic capabilities for biological, environmental and materials sciences

Bionanoprobe Publications

Publications 2016:(3)

2D/3D cryo X-ray fluorescence imaging at the Bionanoprobe at the Advanced Photon Source

S. Chen, T. Paunesku, Y. Yuan, J. Deng, Q. Jin, Y. P. Hong, D. J. Vine, B. Lai, C. Flachenecker, B. Horberger, K. Brister, C. Jacobsen, G. E. Woloschak, and S. Vogt, AIP Conference Proceedings 1696, 020028 (2016). doi: 10.1063/1.4937522

"Advances and challenges in cryo ptychography at the Advanced Photon Source"
J. Deng, D.J. Vine, S. Chen, Y.S.G. Nashed, Q. Jin, T. Peterka, S. Vogt, C. Jacobsen, XRM 2014: Proceedings of the 12th International Conference on X-ray Microscopy  1696,  020030-1 - 020030-1 (2016) DOI: 10.1063/1.4937524

"2D/3D cryo x-ray fluorescence imaging at the bionanoprobe at the advanced photon source"
S. Chen, T. Paunesku, Y. Yuan, J. Deng, Q. Jin, Y.P. Hong, D.J. Vine, B. Lai, C. Flachenecker, B. Hornberger, K. Brister, C. Jacobsen, G.E. Woloschak, S. Vogt, , XRM 2014: Proceedings of the 12th International Conference on X-ray Microscopy  1696,  020028-1 - 020028-5 (2016) DOI: 10.1063/1.4937522


Publications 2015:(10)

Simultaneous X-ray nano-ptychographic and fluorescence microscopy at the Bionanoprobe

S. Chen, J. Deng, D. J. Vine, Y. S. G. Nashed, Q. Jin, T. Peterka, C. Jacobsen, and S. Vogt, SPIE Optical Engineering+Application, 9592, 95920I-6 (2015). doi: 10.1117/12.2190672

A new workflow for X-ray fluorescence tomography: MapstoTomoPy

Y. P. Hong, S. Chen, and C. Jacobsen, SPIE Optical Engineering+Application, 9592, 95920W-8 (2015).  doi: 10.1117/12.2194162

Opportunities and limitations for combined fly-scan ptychography and fluorescence microscopy

J. Deng, D. J. Vine, S. Chen, Y. S. G. Nashed, T. Peterka, R. Ross, S. Vogt, and C. Jacobsen, SPIE Optical Engineering+Application, 9592, 95920U-9 (2015). doi: 10.1117/12.2190749

The Bionanoprobe: synchrotron-based hard X-ray fluorescence microscopy for 2D/3D trace element mapping

S. Chen, T. Paunesku, Y. Yuan, Q. Jin, L. Finney, B. Hornberger, C. Flachenecker, B. Lai, K. Brister, C. Jacobsen, G. Woloschak, and S. Vogt, Micros Today, 23(3), 26-29 (2015). doi: 10.1017/S1551929515000401

Alpha-synuclein regulates neuronal levels of manganese and calcium

T. Dučić, E. Carboni, B. Lai, S. Chen, B. Michalke, D. F. Lázaro, T. F. Outeiro, M, Bähr, E. Barski, and P. Lingor, ACS Chem Neurosci, 6(10), 1769–1779 (2015). doi: 10.1021/acschemneuro.5b00093

Continuous motion scan ptychography: characterization for increased speed in coherent X-ray imaging

J. Deng, Y. S. G. Nashed, S. Chen, N. W. Phillips, T. Peterka, R. Ross, S. Vogt, C. Jacobsen, and D. Vine, Optics Express, 23(5), 5438-14 (2015). doi: 10.1364/OE.23.005438

Ultraviolet germicidal irradiation and its effects on elemental distributions in mouse embryonic fibroblast cells in X-ray fluorescence microanalysis

Q. Jin, S. Vogt, B. Lai, S. Chen, L. Finney, S. C. Gleber, J. Ward, J. Deng, R. Mak, N. Moonier, and C. Jacobsen , PloS ONE, 10(2), e0117437-14 (2015). doi: 10.1371/journal.pone.0117437

Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

E. Que, R. Bleher, F. Duncan, B. Kong, S.-C. Gleber, S. Vogt, S. Chen, S. Garwin, A. Bayer, V. Dravid, T. Woodruff, and T. O’Halloran, Nature Chemistry, 7, 130-139 (2015). doi: 10.1038/NCHEM.2133

High-resolution elemental mapping of human placental chorionic villi using synchrotron X-ray fluorescence spectroscopy

T. Punshon, S. Chen, L. Finney, L. Howard, B. P. Jackson, M. R. Karagas, and Kim Ornvold, Anal Bioanal Chem, 407(22), 6839-50 (2015). doi: 10.1007/s00216-015-8861-5

Simultaneous cryo X-ray ptychographic and fluorescence microscopy of green algae

J. Deng, D. Vine, S. Chen, Y. S. G. Nashed, Q. Jin, N. W. Phillips, T. Peterka, R. Ross, S. Vogt, and C. Jacobsen, , Proc Natl Acad Sci USA, 112(8), 2314-19 (2015). doi:10.1073/pnas.1413003112

 


Publications 2014:(3)

"The Bionanoprobe: hard X-ray fluorescence nanoprobe with cryogenic capabilities"                            

S. Chen, J. Deng, Y. Yuan, C. Flachenecker, R. Mak, B. Hornberger, Q. Jin, D. Shu, B. Lai, J. Maser, C. Roehrig, T. Paunesku, S. C. Gleber, D. J. Vine, L. Finney, J. VonOsinski, M. Bolbat, I. Spink, Z. Chen, J. Steele, D. Trapp, J. Irwin, M. Feser, E. Snyder, K. Brister, C. Jacobsen, G. Woloschak, and S. Vogt, Journal of Synchrotron Radiation, 21, 66-75 (2014). doi: 10.1107/S1600577513029676

Fluorescence micro-tomography of frozen-hydrated whole cells using the Bionanoprobe

S. Chen, C. Flachenecker, T. Paunesku, Y. Yuan, W. Liu, J. Deng, Q. Jin, R. Mak, B. Lai, B. Hornberger, C. Roehrig, J. VonOsinski, M. Bolbat, J. Maser, D. Shu, S. C. Gleber, L. Finney, K. Brister, C. Jacobsen, G. Woloschak, and S. Vogt, Microscopy and Microanalysis, 20 (Suppl 3), 668-669, (2014). doi: 10.1017/S1431927614005066

Biological X-ray fluorescence microscopy: advanced and unique Opportunities

S. Vogt, S. C. Gleber, Q. Jin, S. Chen, L. Finney, C. Jacobsen, M. Ralle, C. Fahrni, and D. Mustafi, Microscopy and Microanalysis, 20 (Suppl 3), 1306-1307 (2014). doi: 10.1017/S1431927614008265


Publications 2013: (2)

EGFR targeted nuclear delivery and high resolution whole cell hard X-ray imaging of Fe3O4@TiO2 nanoparticles in cancer cells

Y. Yuan, S. Chen, T. Paunesku, S.-C. Gleber, W. Liu, C.B. Doty, R. Mak, J. Deng, Q. Jin, B. Lai, K. Brister, C. Flachenecker, C. Jacobsen, S. Vogt, and G. Woloschak, ACS Nano, 7(12), 10502-10507 (2013). doi: 10.1021/nn4033294

Sub-100-nm 3D-elemental mapping of frozen-hydrated cells using the Bionanoprobe

S. Chen, Y. Yuan, J. Deng, R. Mak, Q. Jin, T. Paunesku, S. C. Gleber, D. Vine, C. Flachenecker, B. Hornberger, D. Shu, B. Lai, J. Maser, L. Finney, C. Roehrig, J. VonOsinski, M. Bolbat, K. Brister, C. Jacobsen, G. Woloschak, and S. Vogt, Proc. SPIE 8851, X-ray Nanoimaging: Instruments and Methods, 885102 (2013). doi:10.1117/12.2025169